Description
Anti-Sm (Smith) – antibodies to U1-, U2-, U4-ribonucleoproteins – are specific for systemic lupus erythematosus (SLE). They are rarely found in other connective tissue diseases and are one of the diagnostic criteria for SLE. However, the concentration of anti-Sm does not correlate with the activity of systemic lupus erythematosus. Antibodies to RNP antigens (anti-ribonucleoprotein) are antibodies to the protein components of small nuclear nucleotide – U1-RNA. They are detected in mixed connective tissue diseases (Sharp's syndrome), less frequently in systemic lupus erythematosus and other rheumatic diseases.
Period of execution
Within 8 days. The specified time does not include the day of biomaterial collection
Biomaterial type