Description
The major outer membrane protein (MOMP) of Chlamydia trachomatis is a component of the cell wall of reticulate and elementary bodies. It is synthesized during all phases of the chlamydial developmental cycle in productive infection. It accounts for 60% of the cell wall proteins. The Pgp3 protein is encoded by the chlamydial common plasmid and is responsible for virulence and the ability of the bacteria to cause ascending infection. It is produced into the cytosol of the infected cell at a late stage of infection. Upon lysis of the affected cell, Pgp3 neutralizes the anti-chlamydial activity of the immune system, thereby protecting chlamydia and promoting their dissemination throughout the human body. IgG class antibodies to Pgp3 appear 3-4 weeks after the onset of the disease. MOMP and Pgp3 are species-specific, which excludes the possibility of cross-reactions in the presence of other chlamydial species.
The test is recommended for the diagnosis of urogenital chlamydiosis in latent, asymptomatic disease, as well as in cases with a pronounced clinical picture.
Period of execution
Within 6 days. The specified time does not include the day of biomaterial collection
Biomaterial type