Anti-Cardiolipin Antibodies, IgG and IgM

Anti-cardiolipin antibodies represent the main fraction of antibodies to cell membrane phospholipids, which is a leading indicator of the presence of antiphospholipid syndrome. A certain level of these antibodies is present in the blood of healthy people, but when it increases, a qualitatively new state arises in the hemostasis system. These antibodies interact with the phospholipids of platelet and vascular endothelial cell membranes, causing their destruction and promoting the occurrence of thromboses and embolisms. People with elevated concentrations of anti-cardiolipin antibodies are considered at risk for thrombosis in various diseases. In antiphospholipid syndrome, IgG class antibodies are more often detected. IgM class antibodies respond most quickly to effective treatment of antiphospholipid syndrome (their level decreases). In low concentrations, IgM class anti-cardiolipin antibodies may be present in rheumatoid arthritis, Sjogren's syndrome, drug-induced lupus erythematosus, Lyme disease, and syphilis.

Within 8 days. The specified time does not include the day of biomaterial collection