Description
The presence of a mutation in the c-KIT gene and the presence of a mutation in the PDGFRa gene are predictors of response to imatinib therapy in patients with gastrointestinal stromal tumors (in unresectable tumors, recurrence, or metastatic disease). In addition, the presence of a mutation in the PDGFRa gene is a predictor of response to imatinib therapy in patients with cutaneous melanomas, mucosal melanomas, and acral lentiginous melanomas (stages III (unresectable) and IV).
Test composition
12-299 Detection of c-KIT gene mutations in tumor tissues
12-300 Detection of PDGFRa gene mutations in tumor tissues
Period of execution
Within 12 days. The specified time does not include the day of biomaterial collection
Biomaterial type
- Tissue sample
- Tissue sample in paraffin block