Description
Sodium is the main cation of the extracellular fluid; it maintains osmotic pressure, determines water movement, and participates in the regulation of acid-base balance, neuromuscular excitability, and the transmission of excitation along neuromuscular fibers. Sodium preserves and maintains the stability of the bioelectric potential of cell membranes, potentiates the action of adrenaline, and affects the magnitude of vascular tone. It is contained in the body mainly in the form of ions (up to 85%). The stability of sodium concentration in plasma depends on the secretion of adrenal cortex hormones and the activity of the renin-angiotensin-aldosterone system; gastrin, secretin, cholecystokinin, and prostaglandins influence sodium absorption in the intestine. Increased levels are observed in acute and chronic renal failure, adrenal cortex hyperfunction, conditions accompanied by significant fluid loss (diabetes insipidus, vomiting, diarrhea), brain injuries and tumors, and amyloidosis.
A decrease is possible in acute adrenal cortex insufficiency, hypothyroidism, chronic pyelonephritis, hyperglycemia, hypopituitarism, liver cirrhosis, kwashiorkor, and burn disease.
Indications for analysis:
1. Diagnosis of adrenal cortex dysfunctions
2. Diagnosis of endocrine diseases
3. Diagnosis of malignant brain neoplasms
4. Diagnosis of kidney diseases
Period of execution
By 00:00 the next day. The specified time does not include the day of biomaterial collection
Biomaterial type