Parvovirus B19, DNA [Real-time PCR]

Parvovirus B19 is a DNA-containing virus from the parvovirus family that is pathogenic to humans. Depending on the hematological and immunological status of the patient, the clinical picture of infection can vary within wide limits: from asymptomatic erythroid aplasia to chronic anemia. The virus is found worldwide and is quite widespread. Antibodies against this virus are detected in 2-15% of children and in more than 85% of elderly people. The virus spreads mainly by airborne droplets, but infection is also possible via parenteral administration of donor blood or its components and during organ transplantation. In addition, vertical transmission of the virus from an infected mother to the fetus occurs in approximately 30% of cases. In healthy children, the infection often manifests only as a non-dangerous erythema infectiosum or proceeds asymptomatically or non-specifically. Erythema infectiosum is the most frequent manifestation of parvovirus infection in children. It is a distinctly discernible rash, which may be preceded by general symptoms. The rash on the face can be intensely red ("slapped cheek" syndrome). A symmetrical, maculopapular, reticular ("lace-like") rash appears on the trunk with a tendency to spread to the arms, thighs, and buttocks. In adults, parvovirus infection most often manifests as arthralgia and arthritis, while skin lesions are less common. More rare symptoms include thrombocytopenia, neurological symptoms, and myocarditis.

Within 10 days. The specified time does not include the day of biomaterial collection