Description
Age-Related Macular Degeneration (AMD) is one of the most common eye diseases and is the leading cause of vision loss in people predominantly over the age of 50.
The cause of vision decline is the gradual deterioration of cells in the macula. The macula (yellow spot) is an important area of the eye's retina responsible for the sharpness and acuity of central vision needed for reading, writing, identifying faces, or driving a car.
In some people, degenerative changes develop so slowly that they have little effect on vision during the aging process. But in others, the disease progresses quite quickly and can lead to vision loss in one or both eyes.
With age, the eye's defense system becomes increasingly vulnerable. Increased risk factors also include: smoking, unbalanced diet, excess weight, light skin and blue iris color, exposure to ultraviolet radiation, presence of atherosclerosis, cases of central vision loss among close relatives, as in many cases there is a genetic predisposition for the disease.
It is very important to start disease prevention as early as possible, due to the fact that macular degeneration is an irreversible process, and disease progression can lead to partial vision loss or even total blindness. Early diagnosis and subsequent treatment, if indicated, can help prevent further deterioration of vision.
The study includes two genetic markers determining genetic predisposition to age-related macular degeneration: ARMS2 (G205T) and CFH (C1204T).
The analysis result provides a conclusion identifying the presence or absence of genetic predisposition to age-related macular degeneration and recommendations.
Period of execution
Within 11 days. The specified time does not include the day of biomaterial collection
Biomaterial type
- Buccal (cheek) epithelium
- Venous blood