Description
Opisthorchiasis is a helminthic invasion caused by Opisthorchis felineus, a parasite of the liver fluke class, also known as the Siberian or cat fluke. The disease is characterized by damage to the liver and gallbladder. Upon contact with Opisthorchis antigens, the immune system begins to produce class M immunoglobulins (IgM). Their synthesis reaches its maximum after 1.5–2 weeks and starts to decline after 3–4 weeks, as class G immunoglobulins (IgG) begin to be produced. The concentration of specific IgG reaches its maximum by 2–3 months from the onset of infection and remains at this level for quite a long time. However, with prolonged disease duration, the level of specific antibodies may decrease below the sensitivity threshold of diagnostic methods due to binding of antibodies with helminth antigens and the formation of circulating immune complexes (CIC). The test is intended for the detection of specific CIC containing Opisthorchis antigens in blood serum.
Period of execution
Within 10 days. The specified time does not include the day of biomaterial collection
Biomaterial type