Description
Water-soluble vitamin contained in large quantities in animal products (meat, fish, liver). Entering the gastrointestinal tract with food, it is absorbed in the ileum with the help of a specific protein – Castle's intrinsic factor. Upon entering the intestinal wall, it binds to another specific protein – transcobalamin, forming a complex that is transported to tissues. The vitamin is deposited in the body primarily in two places – the liver and the spleen. Since the body's reserves of the vitamin are quite large and its elimination from the body occurs slowly, it takes about 5 years of reduced intake to create a significant vitamin deficiency. The functions of cyanocobalamin in the body are diverse. As a coenzyme, it takes part in folic acid metabolism and the synthesis of certain amino acids and nucleotides. Being part of the specific enzyme homocysteine methyltransferase, it indirectly contributes to the synthesis of nerve myelin sheaths. It participates in the synthesis of choline, a precursor of many compounds essential for life. It prevents the occurrence of methylmalonic aciduria, a dangerous pathological condition in children manifested by significant developmental delay.
Vitamin B12 deficiency in the body leads to impaired nervous system function, manifested by serious neurological disorders, impaired hematopoiesis leading to the development of megaloblastic anemia, and impaired cell division of the intestinal epithelium and oral cavity epithelium.
Period of execution
By 12 hours. The specified time does not include the day of biomaterial collection
Biomaterial type